ONCOGENES
 
Category I. Growth factors

   PDGF-¥âchain      sis: v-sis of simian sarcoma virus
   FGF               hst-1: A human oncogene activated by DNA rearrangements in
                            gene transfer experiments that encodes a member of
                            the fibroblast growth factor family.
                     int-1: v-onc of retroviral insertional mutagenesis
                            in mouse mammary carcinoma

Category II. Growth factor receptors

   EGFR              erb-B: v-erb-B of avian erythroblastosis virus
                     erb-B2(neu): (no v-onc)
   CSF-1-receptor    fms: v-fms of feline McDonough sarcoma virus

Category III. Proteins involved in signal transduction

   GTP-binding       H-ras: v-onc of Harvey murine (rat) sarcoma virus
                     K-ras: v-onc of Kirsten murine (rat) sarcoma virus
                     N-ras: (no v-onc) of human neuroblastoma

   Non-receptor      abl: v-abl of Abelson murine leukemia virus
   tyrosine kinase   src: v-src of Rous sarcoma virus (pronounced 'sa:k)

Category IV. Nuclear regulatory proteins

   Transcriptional   jun: v-jun of avian sarcoma virus 17 (ju-nana)
   activator         myc: v-myc of avian myelocytomatosis virus
                     N-myc: (no v-onc) of human neuroblastoma
                     L-myc: (no v-onc) of human small cell lung ca
                     fos: v-fos of FBJ murine osteosarcoma virus
                      myb: v-myb of avian myeloblastomatosis virus

Category V. Cell Cycle Regulators

   Cyclins

   Cyclin-dependent kinases