Soh, Jae-Mog
Title:Assistant Professor
Affiliation: Department of Biology, Chonnam National University
Degree: Ph.D. Univ. Med. Den. of N.J., U.S.A.
Address: Department of Biology, Chonnam National University, Kwangju,500-757
Tel.:+82-62-530-3399
FAX:+82-62-530-3409
Email:jmsoh@chonnam.chonnam.ac.kr

 

Our research topics include the study of molecular mechanisms of spermatogenesis in rat testis. To this end we are studying the regulation mechanism of steroidogenesis in Leydig cells and looking for novel gene(s) specifically expressed in adult testis. The roles of those testis-specific genes are being examined in the context of cell-cell interactions within the testis. We are interested in the expression control of the Steroidogenic Acute Regulatory Protein (StAR) gene and elucidatation of action mechanism of StAR protein.

 

  1. Lee HK, Yoo MS, Choi HS, Kwon HB, Soh J (1999) Retinoic acids up-regulate steroidogenic acute regulatory protein gene. Mol Cell Endocrinol.148(1-2):1-10
  2. Kim MY, Lee HK, Park JS, Park SH, Kwon HB, Soh J (1999) Identification of a zeta-crystallin (quinone reductase)-like 1 gene (CRYZL1) mapped to human chromosomed 21q22.1. Genomics, 57(1):156-9
  3. Lee SK, Na SY, Kim HJ, Soh J, Choi HS, Lee JW (1998) Identification of critical residues for heterodimerization within the ligand-binding domain of retinoid X receptor. Mol Endocrinol., 12(3):325-32
  4. Lee HK, Lee YK, Park SH, Kim YS, Park SH, Lee JW, Kwon HB, Soh J, Moore DD, Choi HS (1998) Structure and expression of the orphan nuclear receptor SHP gene. J. Biol. Chem., 273(23):14398-402
  5. Lee, H.-K., Lee, Y.-K., Park, S-H., Kim, Y.-S., Park, S.H., Lee, J.W., Kwon, H.B., Soh. J., Moore, D.D., Choi, H.-H. (1998) Structure and expression of the orphan nuclear receptor SHP gene. J. Biol. Chem. 273, 14398-14402
  6. Lee, H.-K., Ahn, R. S., Kwon, H.-B., and Soh, J. (1997) Nucleotide sequence of rat steroidogenic acute regulatory protein complementary DNA. Biochem. Biophysic. Res. Com. 230: 528-532
  7. Kim, M.-Y., Kwon, H.-B., and Soh, J. (1997) Characterization of four yeast artificial chromosome clones mapped to human chromosome 21q22.1 with eight markers.Molecules and Cells 7: 526-531
  8. Ahn, R. S., Soh, J., Im, W.-B., Ra, C. H., and Kwon, H. B. (1996) Development of steroidogenic capacity during follicle growth in Amphibian ovarian follicles. Korean J. Zool. 39: 257-265
  9. Chang, K. J., Ra, C. H., Soh, J., Lee, W. K., and Kwon, H. B. (1996) Induction of oocyte ovulation and prostaglandin synthesis by gonadotropin and phobol ester in vitro in amphibian (Rana nigromaculata) ovarian follicles. Korean J. Zool. 39: 266-272
  10. Ahn, R. S., Soh, J., Kwon, H. B. (1996) Roles of theca and graulosa cells in follicular steroidogenesis in Rana dybowskii. Korean J. Zool. 39: 273-281
  11. Soh, J., Mariano, T. M., Bradshaw, G., Donnelly, R. J. and Pestka, S. (1994) Generation of random internal deletion derivatives of YACs by homologous targeting to Alu sequences. DNA and Cell Biology 13: 301-309
  12. Cook, J. R., Emanuel, S. L., Donnelly, R. J., Soh, J., Mariano, T. M., Schwartz, B., Rhee, S. and Pestka, S. (1994) Localization of the human interferon-gamma receptor accessory factor gene and discovery of a new accessory factor by chromosomal fragmentation. J. Biol. Chem. 269: 7013-7018
  13. Soh, J., Donnelly, R. J., Kotenko, S., Mariano, T. M., Cook, J. R., Wang, N., Emanuel, S., Schwartz, B., Miki, T., and Pestka, S. (1994) Identification and sequence of an accessoryy factor required for activation of the human interferon gamma receptor. Cell 76: 793-802
  14. Soh, J., Mariano, T. M., Lim, J.-K., Izotova, L., Mirochnitchenko, O., Schwartz, B., Langer, J.A., and Pestka, S. (1994) Expression of a functional type ¥°human interferon receptor in hamster cells: Application of functional YAC screening. J. Biol. Chem. 269: 18102-18110
  15. Cleary, C. M., Donnelly, R. J., Soh, J., Mariano, T. M., and Pestka, S. (1994) Knockout and reconstitution of a functional human type I interferon receptor complex. J. Biol. Chem. 269: 18747-18749