전남대학교 치과대학 조교수

연구실 (062) 530-4852
실험실 (062) 530-4850
FAX ;;;;(062) 530-4809
E-mail : shohk@chonnam.ac.kr

1993. 9. - 1996. 8. 연세대학교 산업기술연구소 연구원
1996. 9. - 1997. 8. 연세대학교 생물산업소재연구센터 연구원
1997. 7. - 1997. 8. 한국 생명공학 벤처산업연구회 회장
1997. 9. - 2000. 2. Postdoctor,
Department of Oral Biology,
School of Dental Medicine,
State University of New York at Buffalo, U.S.A.
2000. 3. - 2001. 6. 연세대학교 치과대학 구강생물학교실 연구강사
2001. 7. - 2003. 2. 연세대학교 치과대학 구강생물학교실 계약교수
2003. 2. - 현재 전남대학교 치과대학 구강미생물학교실 전임강사

1995. 5. 방사성동위원소 취급자 일반면허 (과학기술처)

1983. 2. 서울 대일고등학교 졸업
1991. 2. 연세대학교 공과대학 식품공학과 졸업 (공학사)
1993. 8. 연세대학교 대학원 식품공학과 졸업 (공학석사, 미생물학)
1997. 8. 연세대학교 대학원 식품생물공학과 졸업 (공학박사, 미생물학)

    ACADEMIC ACTIVITIES

한국산업미생물학회 (1991)
한국식품과학회 (1991)
대한미생물학회 (2000)
대한구강생물학회 (2000)
대한생리학회 (2001)

    RESEARCH TOPICS

Signaling in oral biofilm
Porphyromonas gingivalis GTPase
Interactions between oral microorganisms
Volume regulations in osteoblast and osteoclast

 

    RESEARCH IN PROGRESS - IN PREPARATION

Inhibition of 1α,25(OH)2D3 induced osteoclastogenesis by hypertonic volume change of mouse osteoblastic cells.

Regulatory mechanism of 1α,25(OH)₂D₃-induced osteoclastogenesis by FGF-2.

Down-Regulation of Osteoclastogenesis by Mechanical Stretch of Human Periodontal Ligament Cells.

Anticariogenic Effect of Lytic Enzymes Produced from Microorganism in Soil.

Chlorine dioxide containing mouthwash.

Xylitol in osteoclastogenesis.

Characteristics and lytic mode of Streptococcus mutans cell wall hydrolase.

    RESEARCH IN PROGRESS - SUBMITTED

Ohk SH, Nam SW, Bai DH. Purification and Characteristics of Streptococcus mutans Cell Wall Lytic Enzyme Produced by Bacillus alcalophilumutanlysis YU5215. J Microbiol Biotechnol

Ohk SH, Nam SW, Bai DH. Mechanism and chemical properties of Streptococcus mutans Cell Wall Lytic Enzyme Produced by Bacillus alcalophilumutanlysis YU5215. Kor J Appl Microbiol Biotechnol

Choi BK, Ohk SH, Kang JH, Lee HJ, Jin SW, Lee SI, Yoo YJ. Effect of sonicates of Treponema denticola on osteoblast and osteoclast differentiation. Arch Oral Biol

Lee HA, Kim EY, Nam MY, Ohk SH, Seo JT, Lee SI. Inhibitory effect of NKCC inactivation on osteoclast differentiation induced by vitamin D3. Exp Physiol

    PUBLICATIONS - JOURNALS (1997.1 ~ 2006.2)

정현주, 전옥순, 김보혜, 남미영, 이현아, 유윤정, 서정택, 신동민, 옥승호, 이승일. Hypertonicity down-regulates the 1α,25(OH)2 vitaminD3-induced osteoclastogenesis via modulation of RANKL expression in osteoblast. International Journal of Oral Biology 2005, 30(1), 23 - 30.

Kim JY, Cho SW, Song WC, Lee MJ, J Cai, Ohk SH, Song HK, A Degan, Jung HS. Formation of spacing pattern and morphogenesis of chick feather buds is regulated by cytoskeletal structures. Differentiation 2005, 73(5), 240-8.

Lee HA, Jeong H,  Kim EY, Nam MY,  Yoo YJ,  Seo JT, SHin DM,  Ohk SH,  Lee SI. Bumetanide, the specific inhibitor of Na+-K+-2Cl- cotransporter, inhibits 1α,25-dihydroxyvitamin D3-induced osteoclastogenesis in a mouse co-culture system. Exp Physiol 2003;88(5):2558-2593.

Choi BK, Kang JH, Jin SW, Ohk SH, Lee SI, Yoo YJ. Effect of sonicate of Treponema denticola on osteoblast differentiation. 대한치주과학회지 2003;33(1):79-89.

Chang H, Lee JI, Shin DM, Ohk SH, Lee SI. Effect of Insulin on the Regulation of Na/K/Cl Cotransporter (NKCC2) in HEK293 Cells. International Journal of Oral Biology 2002;27: 129-134.

Ohk SH, Yeo IH, Yoo YJ, Kim BK, Bai DH. Cloning and expression of a yeast cell wall hydrolase gene (ycl) from alkalophilic Bacillus alcalophilus subsp. YB380. J Microbiol Biotechnol 2001;11(3):508-514.

Choi BK, Ohk SH, Lee HJ, Kang JH, Jeon GJ, Yoo YJ. Effects of whole cell sonicates of Treponema lecithinolyticum on osteoclast differentiation. J Periodontol 2001;72(9):1172-1177.

Ohk, SH, Yoo YJ, Bai DH. Purification and characterization of Streptococcus mutans cell wall hydrolase from Bacillus subtilis YL-1004. J Microbiol Biotechnol 2001;11(6):957-963.

Bae VD, Ohk SH, Kuramitsu HK. Protein interactions of SGP, an essential Streptococcus mutans GTPase, revealed by biochemical and yeast two-hybrid system analyses. FEMS Microbiology Letters 2000;184:149-153.

박시형, 윤상웅, 박정민, 옥승호, 유주현, 배동훈. Aspergillus sp. F184가 생산하는 Xanthine Oxidase 저해제에 관한 연구. Kor J Appl Microbiol Biotechnol 2000;28(2):92-96.

Ohk SH, Kuramitsu HK. A novel antibacterial agent derived from the C-terminal domain of Streptococcus mutans GTP-binding protein. Journal of Antimicrobial Chemotherapy 2000;46(1): 95-99.

김재우, 이현정, 강정화, 옥승호, 최봉규, 유윤정, 조규성, 최성호. Cyclosporin A가 in vitro에서 조골세포에 미치는 영향. 대한치주과학회지 2000;30(4):747-756.

유윤정, 이현정, 임소형, 강정화, 이은희, 옥승호, 최봉규, 전길자. 녹용 추출물에 의한 MC3T3세포 의 분화 촉진. 대한치주과학회지 2000;30(4):885-893.

Kim SY, Ohk SH, Bai DH, Yu JH. Purification and properties of bacteriolytic enzymes from Bacillus licheniformis YS-1005 against Streptococcus mutans. Biosci Biotechnol Biochem 1999;63:73-77.

Choi YS, Ohk SH, Yu JH and Bai DH. Properties of Biopolymer YU-122 from Metarrhizium anisopliae (Metschn.) Sorok Korean J Food Sci Technol 1997;29:138-144.

Choi YS, Ohk SH, Yu JH and Bai DH. Production of Biopolymer YU-122 from Metarrhizium anisopliae (Metschn.) Sorok Kor J Appl Microbiol Biotechnol 1997;25:82-88.

Lee BY, Ohk SH, Kim SY, Bai DH, Yu JH, Yoo SK. Purification of a bacteriolytic enzyme from Bacillus sp. active against Streptococcus mutans. Biotechnology Techniques 1997;11(5): 283-285.

PRESENTATION ( 2000.1 ~ 2005.2 )