전남대학교 치과대학 조교수

연구실 (062) 220-4433
FAX ;;;;(062) 227-4008
E-mail : jtkoh@chonnam.ac.kr

1992. 3. - 1996. 2. 전남대학교 치과대학 조교
1996. 5. - 1999. 4. 전남장성군 보건의료원 (공중보건의)
1999. 5. - 2001. 2. 전남대학교 치과대학 조교
2001. 3. - 전남대학교 치과대학 전임강사
2003. 4. - 현재 전남대학교 치과대학 조교수

1986. 2. 광주 송원고 졸업
1992. 2. 전남대학교 치과대학 졸업
1994. 2. 전남대학교 대학원 치의학석사
1996. 2. 전남대학교 대학원 치의학박사

    ACADEMIC ACTIVITIES

대한구강생물학회 (1995)
대한약리학회 (1992)
악안면골연구회 (1995)

    RESEARCH TOPICS

Molecular bone biology; Cloning and characterization of the bone-specific genes and its related genes.
Molecular cloning and characterization of brain-specific angiogenesis inhibitor genes (BAI-1,2) in the mouse brain

 

    RESEARCH IN PROGRESS - IN PREPARATION

Roles of angiogenic and angiostatic genes in cyclosporin-induced gingival overgrowth of rats.

Expression and activation of aquaporin (water channel) and its alteration in impaired salivary secretion

    PUBLICATIONS - JOURNALS (1998.1 ~ 2006.2)

HJ Kim, SH Kim, WJ Kim, MS Kim, EJ Lee, HG Oh, WM Oh, SW Park, GJ Lee, NG Choi, JT Koh, DB Dinh, RR Hardin, K Johnson, VL Sylvia, JP Schmitz, DD Dean. Varying Ti-6Al-4V surface roughness induces different early morphologic and molecular responses in MG63 osteoblast-like cells. J Biomed Mater Res A 2005;74(3):366-73.

MS Kim, SH Kim, WJ Kim, HJ Kim, IN Hoang, WM Oh, JT Koh, Ho Park, JY Jeong, EJ Lee, JY Koh, BY Kim, PH Jensen. Caracterization of the TSU-PR1 cell line by chromosome painting and flow cytometry. CANCER GENETICS AND CYTOGENETICS 2005;163(1):17-22.

HJ Kim, SH Kim, WJ Kim, MS Kim, EJ Lee, HG Oh, WM Oh, SW Park, GJ Lee, NG Choi, JT Koh, DB Dinh, RR Hardin, K Johnson, VL Sylvia, JP Schmitz, DD Dean. Varying Ti-6Al-4V surface roughness induces different early morphologic and molecular responses in MG63 osteoblast-like cells. J Biomed Mater Res A 2005;74(3):366-73.

Zhao M, Zhao Z, Koh JT, Jin T, Franceschi RT. Combinatorial gene therapy for bone regeneration: cooperative interactions between adenovirus vectors expressing bone morphogenetic proteins 2, 4, and 7. J Cell Biochem 2005;95(1):1-16.

MS Kim, SH Kim, WJ Kim, HJ Kim, IN Hoang, WM Oh, JT Koh, Ho Park, JY Jeong, EJ Lee, JY Koh, BY Kim, PH Jensen. Caracterization of the TSU-PR1 cell line by chromosome painting and flow cytometry. CANCER GENETICS AND CYTOGENETICS 2005;163(1):17-22.

HJ Kim, SH Kim, WJ Kim, MS Kim, EJ Lee, HG Oh, WM Oh, SW Park, GJ Lee, NG Choi, JT Koh, DB Dinh, RR Hardin, K Johnson, VL Sylvia, JP Schmitz, DD Dean. Varying Ti-6Al-4V surface roughness induces different early morphologic and molecular responses in MG63 osteoblast-like cells. J Biomed Mater Res A 2005;74(3):366-73.

MS Kim, SH Kim, HJ Kim, IN Hoang, WM Oh, JT Koh, JY Jeong, WJ Kim, EJ Lee, JY Koh, BY Kim, RH Jensen. Characterization of TSU-PR1 cell line by chromosome painting and flow cytometry. Cancer Genetics and Cytogenetics 2005;163:17-22.

고정태, 남승지, 정현주, 김옥수, 김영준, 고정태. 한국인 치주염환자에서의 IL-1 유전자 다변성 연구. 대한치주과학회지 2004;34(3):623-637.

고정태, 정하나, 정현주, 김옥수, 김영준, 김주한. 한국인에서 치주질환과 관상동맥질환의 관련성에 대한 염증표지자와 IL-1유전자 다변성의 영향. 대한치주과학회지 2004;34(3):607-622.

Kim MY, Ahn KY, Lee SM, Koh JT, Chun BJ, Bae CS, Lee KS, Kim KK. The Promoter of Brain-specific Angiogenesis Inhibitor 1-associated Protein 4 Drives Developmentally Targeted Transgene Expression Mainly in Adult Cerebral Cortex and Hippocampus. FEBS Letters 2004;566(3):87-94.

Lee SE, Ryu PY, Kim SY, Kim YR, Koh JT, Kim OJ, Chung SS, Choy HE, Rhee JH. Production of Vibrio Vulnificus Hemolysin in vivo and Its Pathogenic Significance. Biochemical and Biophysical Research Communications 2004;324(1):86-91.

Koh JT, Kook H, Kee HJ, Seo YW, Jeong BC, Lee JH, Kim MY, Yoon KC, Jung S,  Kim KK. Extracellular Fragment of Brain-specific Angiogenesis Inhibitor 1 Suppresses Endothelial Cell Proliferation by Blocking alpha(5)beta(5) Integrin. Experimental Cell Research 2004;294(1):172-184.

Koh JT, Kim OJ, Park YS, Kim SH, Kim WJ, Chung HJ, Lee SE, Jeong BC, Jung JY, Kim KK. Decreased Expressions of Thrombospondin 2 in Cyclosporin A-induced Gingival Overgrowth. Journal of Periodontal Research 2004;39(2):93-100.

Koh JT, Jeong BC, Kim JH, Ahn YK, Lee HS, Baik YH, Kim KK. Changes underlying arrhythmia in the transgenic heart overexpressing Refsum disease gene-associated protein. Biochem Biophys Res Commun. 2004;313(1):156-162.

신인식, 윤상오, 정현주, 고정태. 치은섬유아세포의 MMP발현에 대한 Nitric Oxide의 영향. 대한치주과학회지. 2003;33(2):277-288.

Kee HJ, Koh JT, Yang SY, Lee ZH, Baik YH, Kim KK. A Novel Murine Long-chain Acyl-CoA Synthetase Expressed in Brain Participates in Neuronal Cell Proliferation. Biochemical and biophysical research communications 2003;305(4):925-933.

Kee HJ, Koh JT, Kim MY, Ahn KY, Kim JK, Bae CS, Park SS, Kim KK. Expression of Brain-Specific Angiogenesis Inhibitor 2 (BAI2) in Normal and Ischemic Brain: Involvement of BAI2 in the Ischemia-Induced Brain Angiogenesis. J Cereb Blood Flow Metab 2002;22(9):1054-67.

Kim YC, Koh JT, Shin BA, Ahn KY, Choi BK, Kim CG, Kim KK. An Antisense Construct of Full-Length Human RAD50 cDNA Confers Sensitivity to Ionizing Radiation and Alkylating Agents on Human Cell Lines. Radiation Research 2002;157(1):19-25.

Koh JT, Choi HH, Ahn KY, Kim JU, Kim JH, Chun JY, Baik YH, Kim KK. Cardiac Characteristics of Transgenic Mice Overexpressing Refsum Disease Gene-Associated Protein within the Heart. Biochem Biophys Res Commun 2001;286(5):1107-1116.

Shin BA, Ahn KY, Kook H, Koh JT, Kang IC, Lee HC, Kim KK. Overexpressed Human RAD50 Exhibits Cell Death in a p21(WAF1/CIP1)-dependent Manner: Its Potential Utility in Local Gene Therapy of Tumor. Cell Growth Differ 2001;12(5):243-254.

Jeong JC, Kim SH, Kim HJ, Kim MS, Koh JT, Lee KH, Kim WJ, Oh WM, Lee EJ, Ryu SY. Distribution of nitric oxide synthetase isoforms in perioral exocrine glands in rats. Int J Oral Bio 2001;26(1):15-22.

Koh JT, Lee ZH, Ahn KY, Kim JK, Bae CS, Kim H, Kee HJ, Kim KK. Characterization of mouse brain-specific angiogenesis inhibitor 1 (BAI1) and phytanoyl-CoA alpha-hydroxylase-associated protein 1, a novel BAI1-binding protein. Brain Res Mol Brain Res 2001;87(2):223-237.

Lee JH, Koh JT, Shin BA, Ahn KY, Roh JH, Kim YJ, Kim KK. Comparative study of angiostatic and anti-invasive gene expressions as prognostic factors in gastric cancer. Int J Oncol 2001;18(2):355-361.

김선헌, 김현진, 김민석, 정고훈, 고정태, 이기헌, 김원재, 이은주, 김백윤. 토끼에서 탈회 골편과 골편이식에 의한 골 결손부 재생에 관한 비교 연구. 대한해부학회지 2001; 34(2):193-206.

김선헌, 김민석, 김현진, 한정우, 고정태, 김옥준, 김원재, 오원만. 흰쥐에서 pamidronate와 etidronate가 치아 발육에 미치는 영향. 대한구강해부학회지 2001;25(3):259-270.

Kim KK, Shin BA, Seo KH, Kim PN, Koh JT, Kim JH, Park BR. Molecular cloning and characterization of splice variants of human RAD50 gene. Gene 1999;22;235(1-2):59-67 (IF: 2.258)

Koh JT, Ju JM, Shin DH, Cho HH, Choi BK, Kim JH. Influence of the central benzodiazepinergic system on peripheral cardiovascular regulation. Korean J Physiol Pharmacol 1998;2:287-295

Koh JT, Kook YJ. Natriuresis induced by intracerebroventiricular diazepam in rabbit. Korean J Physiol Pharmacol 1998;2:555-563

PRESENTATION ( 2000.1 ~ 2005.2 )